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Multiple mutations in polyketide synthase led to disruption of Psittacofulvin production across diverse parrot species

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Abstract Polyketide synthases (PKSs) are crucial multidomain enzymes in diverse natural product biosynthesis. Parrots use a type I PKS to produce a unique pigment called psittacofulvin in their feathers. In domesticated budgerigars and lovebirds. the same amino acid substitution (R644W) within malonyl/acetyltransferase (MAT) domain of this enzyme has been shown to cause the blue pheno... https://www.ashleyshomestores.shop/product-category/wide-seat-recliner/
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